• Title of article

    A simple greedy algorithm for reconstructing pedigrees

  • Author/Authors

    Cowell، نويسنده , , Robert G.، نويسنده ,

  • Issue Information
    دوماهنامه با شماره پیاپی سال 2013
  • Pages
    9
  • From page
    55
  • To page
    63
  • Abstract
    This paper introduces a simple greedy algorithm for searching for high likelihood pedigrees using micro-satellite (STR) genotype information on a complete sample of related individuals. The core idea behind the algorithm is not new, but it is believed that putting it into a greedy search setting, and specifically the application to pedigree learning, is novel. The algorithm does not require age or sex information, but this information can be incorporated if desired. The algorithm is applied to human and non-human genetic data and in a simulation study.
  • Keywords
    Pedigree reconstruction , Maximum likelihood pedigree , greedy search
  • Journal title
    Theoretical Population Biology
  • Serial Year
    2013
  • Journal title
    Theoretical Population Biology
  • Record number

    1567619