Title of article
Simple synthesis of mono- and difluoroalanines
Author/Authors
Gerus، نويسنده , , I.I and Kolomeitsev، نويسنده , , A.A and Kolycheva، نويسنده , , M.I and Kukhar، نويسنده , , V.P، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
3
From page
31
To page
33
Abstract
Highly basic tris(diethylamino)-N-methylphosphazene was used for mono- and difluoromethylation of diethyl N-acetylaminomalonate by CH2BrF or CHClF2 in dichloromethane at −40°C. Acidic hydrolysis of fluoromethylated products afforded fluoro- and difluoroalanine, respectively.
Keywords
Tris(diethylamino)-N-methylphosphazene , Fluoromethylation , Difluoromethylation , Fluorinated amino acids
Journal title
Journal of Fluorine Chemistry
Serial Year
2000
Journal title
Journal of Fluorine Chemistry
Record number
1602942
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