Title of article
Synthesis of 4,5-difluoroimidazole
Author/Authors
Dolensky، نويسنده , , Bohumil and Takeuchi، نويسنده , , Yoshio and Cohen، نويسنده , , Louis A and Kirk، نويسنده , , Kenneth L، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
2
From page
147
To page
148
Abstract
5-Fluoroimidazole-4-carboxylic acid ethyl ester was converted to the corresponding hydrazide. Oxidation of the hydrazide to the carbonyl azide and Curtius rearrangement in t-butyl alcohol produced 4-t-butyloxycarbonylamino-5-fluoroimidazole. Dissolution of the t-butyl carbamate in 50% HBF4, in situ diazotation of the resulting amine, and irradiation produced the target compound.
Keywords
Photochemical Schiemann reaction , Fluoroimidazoles
Journal title
Journal of Fluorine Chemistry
Serial Year
2001
Journal title
Journal of Fluorine Chemistry
Record number
1603049
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