Title of article
Polyhalogenated heterocyclic compounds: Part 45. Reactions of perfluoro-(4-isopropylpyridine) with oxygen, nitrogen and carbon nucleophiles
Author/Authors
Chambers، نويسنده , , Richard D. and Hassan، نويسنده , , Mohammed A. and Hoskin، نويسنده , , Philip R. and Kenwright، نويسنده , , Alan and Richmond، نويسنده , , Paul and Sandford، نويسنده , , Graham، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
12
From page
135
To page
146
Abstract
Reactions between perfluoro-(4-isopropylpyridine) (1) and a variety of oxygen-, nitrogen- and carbon-centred nucleophiles are reported. A range of mono-, di- and tri-substituted perfluoro-(4-isopropylpyridine) derivatives were synthesised for which yields and regiochemistry depended on reaction conditions. The barriers to rotation for the perfluoro-isopropyl group in several pyridine systems were measured by 19F NMR spin-saturation transfer experiments.
Keywords
Heterocycles , nucleophilic aromatic substitution , Perfluoro-(4-isopropylpyridine)
Journal title
Journal of Fluorine Chemistry
Serial Year
2001
Journal title
Journal of Fluorine Chemistry
Record number
1603277
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