Title of article
Preparation of δ-fluorinated homoallylic alcohol derivatives via regioselective hydride reduction of allylic alcohol derivatives
Author/Authors
Nakamura، نويسنده , , Yuko and Okada، نويسنده , , Midori and Horikawa، نويسنده , , Hiroaki and Taguchi، نويسنده , , Takeo، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
6
From page
143
To page
148
Abstract
δ-Fluoro and δ,δ-difluorohomoallylic alcohol derivatives can be efficiently prepared by LiAlH4 reduction of the δ,δ-difluoroallylic alcohols and the γ-chlorodifluoromethylallylic alcohols, respectively, through regioselective SN2′ reaction, in which the free hydroxyl group is essential for the reaction to proceed.
Keywords
Difluorohomoallyl alcohol , Fluorohomoallyl alcohol , Trimethylaluminum , Lithiumaluminum hydride
Journal title
Journal of Fluorine Chemistry
Serial Year
2002
Journal title
Journal of Fluorine Chemistry
Record number
1603650
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