Title of article
Synthesis of 2-trifluoromethyl-1(substituted aryl)-4(1H)-quinolones using trifluoroacetamidoyl chlorides
Author/Authors
Lَpez، نويسنده , , Simَn E and Rebollo، نويسنده , , Oscar and Salazar، نويسنده , , José and Charris، نويسنده , , Jaime E and Yلnez، نويسنده , , Cicerَn، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
5
From page
71
To page
75
Abstract
A simple two-step procedure for the preparation of 2-trifluoromethyl-1(substituted aryl)-4(1H)-quinolones utilizing electrophilic trifluoroacetamidoyl chlorides as the starting materials is described. The cyclization of trifluoromethyl enaminone intermediates with potassium carbonate in hot dimethylformamide produce the trifluoromethylated 4(1H)-quinolones in good to excellent yields.
Keywords
4(1H)-quinolone , Trifluoroacetamidoyl chloride , Trifluoromethyl
Journal title
Journal of Fluorine Chemistry
Serial Year
2003
Journal title
Journal of Fluorine Chemistry
Record number
1607412
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