Title of article
Haloacetylated enol ethers: 18: Synthesis of alkyl 6-[azol-3(5)-yl]hexanoates
Author/Authors
Martins، نويسنده , , Marcos A.P. and Bastos، نويسنده , , Giovani P. and Sinhorin، نويسنده , , Adilson P. and Zimmermann، نويسنده , , Nilo E.K. and Rosa، نويسنده , , Adriano and Brondani، نويسنده , , Sergio and Emmerich، نويسنده , , Daniel and Bonacorso، نويسنده , , Helio G. and Zanatta، نويسنده , , Nilo، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
5
From page
249
To page
253
Abstract
A convenient method for the synthesis of eight alkyl 6-[4,5-dihydroisoxazol-3-yl(-pyrazol-3(5)-yl)]hexanoates from the cyclocondensation of methyl 10,10,10-trifluoro[chloro]-9-oxo-7-methoxydec-7-enoates and hydroxylamine hydrochloride or hydrazine hydrochloride, respectively, in ethanol as solvent is reported. The reaction of methyl 10,10,10-trichloro-9-oxo-7-methoxydec-7-enoates with hydrazines furnished the pyrazole derivatives with the simultaneous transformation of trichloromethyl to carboxyl group.
Keywords
4 , pyrazoles , Alkyl hexanoates , 5-Dihydroisoxazoles , Isoxazoles , enones
Journal title
Journal of Fluorine Chemistry
Serial Year
2003
Journal title
Journal of Fluorine Chemistry
Record number
1607789
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