Recycling of fluorinated axially dissymmetric ligand with fluorous solvent

Axially dissymmetric ligand, (Ra)-2,2′-bis[(R)-1-hydroxy-1H-perfluorooctyl]-biphenyl (1), showing a high asymmetric induction, was found to be recovered quantitatively with a fluorous solvent from the reaction mixture owing to its high fluorine content. The recovered ligand 1 was pure enough to be reused without purification. The efficiency of 1 as the chiral ligand was not reduced at all even after seven times recycling.