Title of article
A new synthesis of 2-fluoro-1-naphthols
Author/Authors
Cai، نويسنده , , Xiaohong and Wu، نويسنده , , Kai and Dolbier Jr.، نويسنده , , William R.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
477
To page
480
Abstract
A general synthesis of 2-fluoro-1-naphthols in two steps from 1-indanones is reported. The 1-indanones are first converted to difluoromethyl 2-fluoro-1-napthyl ethers by reaction with difluorocarbene source, trimethylsilyl 2-fluorosulfonyl-2,2-difluoroacetate (TFDA). These ethers are then converted in high yield to the respective naphthols by heating with a mixture of acetic acid and 48% HBr.
Keywords
indanone , Fluoroaromatics , difluorocarbene
Journal title
Journal of Fluorine Chemistry
Serial Year
2005
Journal title
Journal of Fluorine Chemistry
Record number
1608854
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