Title of article
Synthesis and anti-inflammatory activity of fluorinated isocoumarins and 3,4-dihydroisocoumarins
Author/Authors
Qadeer، نويسنده , , Ghulam and Rama، نويسنده , , Nasim Hasan and Garduٌo-Ramيrez، نويسنده , , M.L.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
6
From page
641
To page
646
Abstract
The synthesis of several fluorinated isocoumarins and 3,4-dihydroisocoumarins are described. The structures of the synthesized compounds were confirmed by spectral and elemental analysis. All synthesized compounds were evaluated for their anti-inflammatory and antioxidant activity. These compounds were found to present antioxidant and anti-inflammatory activities. A few of them were found to be significantly active in vivo against ear edema in mice produced by 12-O-tetradecanoylphorbol-13-acetate (TPA) and also good radical scavengers.
Keywords
Synthesis , Fluorinated isocoumarins , 3 , anti-inflammatory activity , 4-Dihydroisocoumarins , antioxidant activity
Journal title
Journal of Fluorine Chemistry
Serial Year
2007
Journal title
Journal of Fluorine Chemistry
Record number
1609684
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