Title of article
Synthesis of (E)- and (Z)-α,β-difluorourocanic acid
Author/Authors
Hajduch، نويسنده , , Jan and Dolensk، نويسنده , , Bohumil and Yoshida، نويسنده , , Shinichi and Fan، نويسنده , , Junfa and Kirk، نويسنده , , Kenneth L.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
7
From page
112
To page
118
Abstract
Horner–Emmons fluoroolefination of an aryl aldehyde followed by introduction of a second fluorine via “FBr” addition provides an original approach to the preparation of 1-alkyl-2-aryl-1,2-difluoroethenes. The utility of this procedure is demonstrated by the preparation of (E and Z)-α,β-difluorourocanic acid.
Keywords
Fluoroimidazole , Urocanic acid , Fluoroolefins , FBr addition , Regiochemistry
Journal title
Journal of Fluorine Chemistry
Serial Year
2008
Journal title
Journal of Fluorine Chemistry
Record number
1610006
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