Title of article
CF3-substituted 1,3-dicarbonyl compounds in the Biginelli reaction promoted by chlorotrimethylsilane
Author/Authors
Sergey V. Ryabukhin، نويسنده , , Sergey V. and Plaskon، نويسنده , , Andrey S. and Ostapchuk، نويسنده , , Eugeniy N. and Volochnyuk، نويسنده , , Dmitriy M. and Shishkin، نويسنده , , Oleg V. and Tolmachev، نويسنده , , Andrey A.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
7
From page
625
To page
631
Abstract
Trifluoromethyl-1,3-diones were investigated as reactants in the Biginelli reaction promoted by Me3SiCl. The dependence of the reaction pathway on the nature of substituent at the α-position to the carbonyl group was established. A set of new CF3-containing dihydropyrimidine(thi)one derivatives was obtained. A number of novel 5-CF3CO dihydropyrimidine(thi)ones were synthesized.
Keywords
3-diones , Biginelli reaction , chlorotrimethylsilane , Thioureas , Ureas , 4-Trifluorometyl-1
Journal title
Journal of Fluorine Chemistry
Serial Year
2008
Journal title
Journal of Fluorine Chemistry
Record number
1610156
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