Title of article
Optically active 4-amino-4-aryl-5,5,5-trifluoropentan-2-ones: Versatile reagents for synthesis of chiral 4-trifluoromethyl-3,4-dihydroazin-2-ones
Author/Authors
Sukach، نويسنده , , Volodymyr A. and Golovach، نويسنده , , Nataliya M. and Melnichenko، نويسنده , , Nina V. and Tsymbal، نويسنده , , Ivan F. and Vovk، نويسنده , , Mykhaylo V.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
7
From page
1180
To page
1186
Abstract
A cyclocondensation of disubstituted (thio)ureas and isocyanates derived from enantiomerically enriched 4-amino-4-aryl-5,5,5-trifluoropentan-2-ones affords a novel synthetic access to chiral 4-trifluoromethyl-substituted 3,4-dihydropyrimidin-2(1H)-(thi)ones and 3,4-dihydro-1,3-oxazin-2-ones, respectively.
Keywords
3 , 4-Dihydropyrimidin-2(1H)-(thi)ones , 3 , 4-Dihydro-1 , 3-oxazin-2-ones , Optically active compounds , ?-Aminoketones , ?-Isocyanatoketones , cyclocondensation
Journal title
Journal of Fluorine Chemistry
Serial Year
2008
Journal title
Journal of Fluorine Chemistry
Record number
1610327
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