Title of article
Three-component synthesis of substituted β-(trifluoromethyl)pyrroles via Grob cyclization of 1,1,1-trifluoro-3-nitrobut-2-ene with 1,3-dicarbonylic compounds and ammonia or primary amines
Author/Authors
Korotaev، نويسنده , , Vladislav Yu. and Barkov، نويسنده , , Alexey Yu. and Kotovich، نويسنده , , Ivan V. and Sosnovskikh، نويسنده , , Vyacheslav Ya.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2012
Pages
6
From page
42
To page
47
Abstract
A variety of substituted β-(trifluoromethyl)pyrroles were easily synthesized in good yields by a one-pot, three-component Grob cyclization of 1,1,1-trifluoro-3-nitrobut-2-ene with 1,3-dicarbonyls (ethyl acetoacetate, acetylacetone, benzoylacetone) and ammonia or primary aliphatic amines.
Keywords
?-(Trifluoroethylidene)nitroethane , 1 , 3-dicarbonyls , Three-component reaction , Grob cyclization , ?-(Trifluoromethyl)pyrroles , Primary amines
Journal title
Journal of Fluorine Chemistry
Serial Year
2012
Journal title
Journal of Fluorine Chemistry
Record number
1611804
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