Title of article
[3+2] Cycloaddition reactions of diethyl (E)-2-fluoromaleate
Author/Authors
Patrick ، نويسنده , , Timothy B. and Shadmehr، نويسنده , , Mehrdad and Khan، نويسنده , , Akbar H. and Singh، نويسنده , , Rajiv K. and Asmelash، نويسنده , , Bethel، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2012
Pages
3
From page
109
To page
111
Abstract
Diethyl E-2-fluoromaleate has been prepared in a pure state in 89% yield by a Horner–Wadsworth–Emmons Wittig procedure. The E configuration was determined by NMR spectroscopy. Diethyl E-2-fluoromaleate undergoes [3+2] cycloadditions with a series of aromatic α-iminoesters and aromatic nitrones. The yields of purified cyclic products ranged from 65 to 80%.
Keywords
Fluorinated pyrrolidine , E-2-Fluoromaleate , proline , Fluorinated isoxazolidines , Iminoester , nitrone , 3 Cycloaddition
Journal title
Journal of Fluorine Chemistry
Serial Year
2012
Journal title
Journal of Fluorine Chemistry
Record number
1611875
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