Title of article
Bromination/desilicobromination of silylated monofluoroalkenes using tetrabutylammonium tribromide under microwave conditions
Author/Authors
Malo-Forest، نويسنده , , Bianca and Roy، نويسنده , , Jessye-Ann and Paquin، نويسنده , , Jean-François، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2013
Pages
4
From page
77
To page
80
Abstract
New conditions for the bromination/desilicobromination of silylated monofluoroalkenes using tetrabutylammonium tribromide under microwave conditions are presented. The reaction is fast (20 min) and provide, after the desilicobromination step, the bromofluoroalkene where the replacement of the silyl group is done with retention of configuration with little or no stereochemical erosion. Isomeric enrichment is even observed in one case. Optimization of the reactions conditions and applications to various substrates are reported.
Keywords
Desilicobromination , Monofluoroalkene , Bromofluoroalkene , Microwave conditions , Bromination , tetrabutylammonium tribromide
Journal title
Journal of Fluorine Chemistry
Serial Year
2013
Journal title
Journal of Fluorine Chemistry
Record number
1611940
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