Title of article
Construction of chiral trifluoromethylated materials by combination of stereochemically predictable SN2′ reaction and Ireland-Claisen rearrangement
Author/Authors
Ichikawa، نويسنده , , Tomoaki and Kawasaki-Takasuka، نويسنده , , Tomoko and Yamada، نويسنده , , Shigeyuki and Yamazaki، نويسنده , , Takashi and Kubota، نويسنده , , Toshio، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2013
Pages
8
From page
38
To page
45
Abstract
We have succeeded in establishment of a novel route for the construction of optically active CF3-containing carboxylic acids in a stereochemically predictable manner starting from easily available mandelic acid by convenient combination of the copper-mediated anti-SN2′ type substitution and Ireland-Claisen rearrangement.
Keywords
Stereodivergent synthesis , Ireland-Claisen rearrangement , 2-Bromo-3 , SN2? reaction , 3-trifluoropropene , Trifluoromethyl group , 3
Journal title
Journal of Fluorine Chemistry
Serial Year
2013
Journal title
Journal of Fluorine Chemistry
Record number
1612038
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