Effect of immunological enhancement of aloe polysaccharide on chickens immunized with Bordetella avium inactivated vaccine

This study was conducted to evaluate the effect of aloe polysaccharide on immune responses of chickens immunized with Bordetella avium (B. avium) vaccine. SPF chickens were randomly divided into 6 groups and vaccinated against B. avium vaccine which respectively contained aloe polysaccharide of three different dosages, propolis and pine pollen polysaccharide. The data showed that aloe polysaccharide significantly enhanced serum and bile antibody level, blood lymphocyte ratio and splenic T lymphocyte proliferation rate in groups I, IV and V. 40 mg/ml of aloe polysaccharide made the vaccine most effective and 20 mg/ml of propolis or 20 mg/ml of pine pollen polysaccharide achieved the same effect. These results suggested that aloe polysaccharide could significantly enhance immune effect of B. avium inactivated vaccine and had important implications for the further use of aloe polysaccharide as a new type of plant-derived immunopotentiator.