Title of article
Asymmetric Mukaiyama aldol reaction of a ketene silyl acetal of thioester catalyzed by a binaphthol–titanium complex in supercritical fluoroform
Author/Authors
Mikami، نويسنده , , Koichi and Matsukawa، نويسنده , , Satoru and Kayaki، نويسنده , , Yoshihito and Ikariya *، نويسنده , , Takao، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
1931
To page
1934
Abstract
The Mukaiyama aldol reaction catalyzed by a binaphthol-derived chiral titanium(IV) complex proceeds smoothly in an unorthodox reaction medium, supercritical fluid (SCF) such as fluoroform (scCHF3). The chemical yield and enantioselectivity of the reaction in SCFs are found to be tuned by changing the supercritical fluids, scCHF3 versus carbon dioxide (scCO2), and adjusting the matched polarities by varying the pressure of CHF3.
Keywords
Asymmetric catalysis , Supercritical fluids , Mukaiyama aldol reaction , chiral Ti catalyst
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1636608
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