Title of article
Polymer-bound TBTU as a new solid-supported reagent for peptide synthesis
Author/Authors
Chinchilla، نويسنده , , Rafael and Dodsworth، نويسنده , , David J and Nلjera، نويسنده , , Carmen and Soriano، نويسنده , , José M، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
2463
To page
2466
Abstract
A new polymer-supported TBTU (P-TBTU) has been prepared from polystyrene-bound 1-hydroxybenzotriazole (P-HOBT) and used efficiently as a solid-supported reagent for peptide-coupling reactions, and is even effective with wet solvents. The P-HOBT can be recovered by simple filtration and reused for the preparation of new P-TBTU.
Keywords
Polymers , Peptides , aminium salts , Coupling reagents
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1636812
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