Title of article
Asymmetric synthesis of 1,3- and 1,3,4-substituted pyrrolidines
Author/Authors
Lin، نويسنده , , Jing and Chan، نويسنده , , Wing-Hong and Lee، نويسنده , , Albert W.M and Wong، نويسنده , , Wai Yeung and Huang، نويسنده , , Pei Qiang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
3
From page
2949
To page
2951
Abstract
Diastereoselective alkylation of N-acylnorbornene sultams 2 afforded a variety of enantiomerically pure products 3a–3e. Reduction with LiAlH4 (LAH) followed by ditosylation furnished chiral 1,4-ditosylates 5a–5e which underwent a cyclization reaction with primary amines to afford chiral 1,3- and 1,3,4-substituted pyrrolidines.
Keywords
cyclization , Pyrrolidines , sultams , asymmetric synthesis
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1637123
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