Title of article
Convenient synthesis of protected primary amines from nitriles
Author/Authors
Caddick، نويسنده , , Stephen and de K. Haynes، نويسنده , , Alexandra K and Judd، نويسنده , , Duncan B and Williams، نويسنده , , Meredith R.V Williams، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
3513
To page
3516
Abstract
Investigations into the use of nickel chloride and sodium borohydride for the reduction of nitriles showed the secondary amine dimers to be the major products under normal conditions. The addition of a suitable trapping agent, such as di-tert-butyl dicarbonate, allowed the isolation of the protected primary amines.
Keywords
Dimerisation , Nitriles , nickel boride , Reduction
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1637465
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