Title of article
RuO4-catalysed oxidative cyclisation of 1,6-dienes to trans-2,6-bis(hydroxymethyl)tetrahydropyranyldiols. A novel stereoselective process
Author/Authors
Piccialli، نويسنده , , Vincenzo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
3
From page
3731
To page
3733
Abstract
RuO4 catalyses the stereoselective oxidative cyclisation of the 1,6-dienes, 7-methyl-1,6-octadiene and 1,6-heptadiene, to the corresponding trans-2,6-bis(hydroxymethyl)tetrahydropyranyldiols, in the presence of NaIO4 as primary oxidant, in EtOAc:CH3CN:H2O (3:3:1) at 0°C for 4 min. A mechanistic hypothesis explaining the observed trans-2,6-stereochemical control is formulated.
Keywords
RuO4 , stereoselective process , trans-THP diols
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1637585
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