• Title of article

    A new synthetic approach for novel C-3 substituted β-lactams

  • Author/Authors

    Madan، نويسنده , , Sachin and Arora، نويسنده , , Renu and Venugopalan، نويسنده , , P and Bari، نويسنده , , S.S، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2000
  • Pages
    5
  • From page
    5577
  • To page
    5581
  • Abstract
    An effective route to novel C-3 substituted β-lactams is described. This involves reaction of a β-lactam carbocation equivalent with active aromatic nucleophiles in the presence of a Lewis acid. The stereospecificity of the formation of mono-substituted products may be rationalised on the basis of the SnCl4 mediated intermediate complex A that reacts via an SN2 mechanism.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2000
  • Journal title
    Tetrahedron Letters
  • Record number

    1638253