Title of article
A proline-catalyzed asymmetric Robinson annulation reaction
Author/Authors
Bui، نويسنده , , Tommy and Barbas III، نويسنده , , Carlos F، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
6951
To page
6954
Abstract
A single-step enantioselective synthesis of the Wieland–Miescher ketone (5) is presented. We show that l-proline as well as a number of other chiral amines can act as catalysts of both steps of the Robinson annulation reaction. Other chiral amines are identified as catalysts of Michael and aldol addition reactions.
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1638746
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