Title of article
A novel highly stereoselective total synthesis of epothilone B and of its (12R,13R) acetonide
Author/Authors
Mulzer، نويسنده , , Johann and Karig، نويسنده , , Gunter and Pojarliev، نويسنده , , Peter، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
7635
To page
7638
Abstract
Stereoselective syntheses of epothilone B (1) and its novel derivative 2 are described. Key steps are the formation of intermediate 3 via Sharpless AD-reaction and Davis–Evans-hydroxylation.
Keywords
asymmetric synthesis , Antitumor compounds , Oxazolidinone , hydroxylation
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1639102
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