Title of article
Conjugate intra- and intermolecular addition mediated by methoxide anion on polymeric support
Author/Authors
Fava، نويسنده , , Cristiana and Galeazzi، نويسنده , , Roberta and Gonzalez-Rosende، نويسنده , , Eugenia Maria and Orena، نويسنده , , Mario، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
8577
To page
8580
Abstract
By treatment with methoxide anion on polymeric support (IRA 900), chiral β-oxo or β-sulphonylamides 2 bearing an α,β-unsaturated ester gave 3,4-disubstituted pyrrolidin-2-ones 3 as easily separable diastereomeric mixtures in good yield and moderate-to-good stereoselection. The polymeric reagent was also effective in promoting both intermolecular conjugate addition and alkylation reactions.
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1639674
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