• Title of article

    Aqueous trifluoroacetic acid—an efficient reagent for exclusively cleaving the 5′-end of 3′,5′-TIPDS protected ribonucleosides

  • Author/Authors

    Zhu، نويسنده , , Xue-Feng and Williams، نويسنده , , Howard J and Scott، نويسنده , , A.Ian، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2000
  • Pages
    5
  • From page
    9541
  • To page
    9545
  • Abstract
    The 5′-silyl ethers of 3′,5′-TIPDS protected nucleosides can be selectively cleaved in excellent yields (95–99%) by treatment with TFA–H2O–THF (1:1:4) at 0°C.
  • Keywords
    nucleosides , Nucleotides , protection groups , Hydrolysis , Cleavage reactions , regiospecificity
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2000
  • Journal title
    Tetrahedron Letters
  • Record number

    1640316

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1640316