Title of article
Diterpenoid pyrones, novel blockers of the voltage-gated potassium channel Kv1.3 from fungal fermentations
Author/Authors
Goetz، نويسنده , , Michael A and Zink، نويسنده , , Deborah L and Dezeny، نويسنده , , Gabe and Dombrowski، نويسنده , , Anne and Polishook، نويسنده , , Jon D and Felix، نويسنده , , John P and Slaughter، نويسنده , , Robert S and Singh، نويسنده , , Sheo B، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
1255
To page
1257
Abstract
The isolation, structure elucidation and chemical modification of nalanthalide, a novel diterpenoid pyrone blocker of the voltage-gated potassium channel Kv1.3 are reported. The structure–activity relationship of the derivatives with respect to various associated biological activities is also discussed.
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1641900
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