Title of article
Palladium-catalyzed cycloisomerization of (Z)-(2-en-4-ynyl)amines: a new synthesis of substituted pyrroles
Author/Authors
Gabriele، نويسنده , , Bartolo and Salerno، نويسنده , , Giuseppe and Fazio، نويسنده , , Alessia and Bossio، نويسنده , , Maria R، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
1339
To page
1341
Abstract
(Z)-(2-En-4-ynyl)amines 1 bearing an internal triple bond undergo smooth cycloisomerization into pyrroles 2 in the presence of catalytic amounts of PdCl2 in conjunction with KCl at 25–100°C in anhydrous N,N-dimethylacetamide. When the triple bond is terminal, spontaneous uncatalyzed cyclization to the corresponding pyrroles takes place.
Keywords
cycloisomerization , enynamines , pyrroles , PALLADIUM
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1641972
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