Title of article
Facile chelation-controlled reductive opening of methoxybenzylidene acetals with Bu3SnH and MgBr2. Regioselective protection strategy as MPM ethers
Author/Authors
Zheng، نويسنده , , Bao-Zhong and Yamauchi، نويسنده , , Megumi and Dei، نويسنده , , Hiroo and Kusaka، نويسنده , , Shin-ichi and Matsui، نويسنده , , Katsuya and Yonemitsu، نويسنده , , Osamu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
5
From page
6441
To page
6445
Abstract
A mild and efficient regioselective reductive opening of methoxybenzylidene acetals using a combination of Bu3SnH and MgBr2·OEt2, mainly via five-membered chelation intermediates is described. This reaction was applied to synthetic intermediates of myriaporon and tedanolide.
Keywords
tri-n-butyltin hydride , Protecting group , benzylidene acetal , Reductive cleavage , chelation , regioselection , magnesium bromide
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1642268
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