Title of article
A new straightforward synthesis of 2,3-aziridino-γ-lactones
Author/Authors
Carole de Saint-Fuscien، نويسنده , , Carole and Tarrade، نويسنده , , Aurélie and Dauban، نويسنده , , Philippe and Dodd، نويسنده , , Robert H، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
5
From page
6393
To page
6397
Abstract
A concise synthesis of 2,3-aziridino-γ-lactones starting from commercially available α,β-dihydroxy-γ-lactones is described. The strategy involves a Michael-type addition of benzylamine onto a key 2-(5H)-furanon-3-yl trifluoromethanesulfonate, followed by in situ cyclization to the aziridine without lactone-ring-opening.
Keywords
aziridine , furanone , Michael-type addition , triflate
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1642744
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