Title of article
A latent aryl hydrazine ‘safety-catch’ linker compatible with N-alkylation
Author/Authors
Berst، نويسنده , , Frédéric and Holmes، نويسنده , , Andrew B and Ladlow، نويسنده , , Mark and Murray، نويسنده , , Peter John، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
5
From page
6649
To page
6653
Abstract
The preparation and use of a latent aryl hydrazine ‘safety-catch’ linker for solid-phase chemistry, which is compatible with N-alkylation, is reported. Its use is exemplified by the preparation of mono-ketopiperazines, whereby release from resin is effected via an intramolecular cyclitive cleavage strategy.
Keywords
solid-phase synthesis , Alkylation , Hydrazines , Cyclisation
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1642872
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