Title of article
First synthesis of segetalin A and analogous cyclohexapeptides
Author/Authors
Sonnet، نويسنده , , Pascal and Petit، نويسنده , , Laurent and Marty، نويسنده , , Danielle and Guillon، نويسنده , , Jean and Rochette، نويسنده , , Jacques and Brion، نويسنده , , Jean-Daniel، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
1681
To page
1683
Abstract
The first synthesis of segetalin A and two analogues is described. Peptide cyclisation was carried out between l-glycine and l-alanine residues in the linear hexapeptide at the final step of the synthesis. Diphenylphosphoryl azide (DPPA) gave the best results as a coupling reagent without epimerisation. The synthesized segetalin A was completely identical to the natural compound with respect to its physicochemical properties.
Keywords
cyclohexapeptides , Segetalin A , Solid-phase peptide synthesis
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1643397
Link To Document