Intramolecular alkene hydroaminations catalyzed by simple amido derivatives of the Group 3 metals

Bis(trimethylsilyl) amides of the type Ln[N(TMS)2]3 have been found to be competent catalysts for representative intramolecular alkene hydroaminations. The catalytic cyclization of an aminodiene proceeds in a stepwise manner to provide the corresponding monocycle and bicycle in a highly stereocontrolled manner.