• Title of article

    Synthesis of phosphinic alanyl-proline surrogates Alaψ(PO2R-CH)Pro as potential inhibitors of the human cyclophilin hCyp-18

  • Author/Authors

    Demange، نويسنده , , Luc and Dugave، نويسنده , , Christophe، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    3
  • From page
    6295
  • To page
    6297
  • Abstract
    Pseudopeptides containing the phosphinic analogue of the alanyl-proline motif Alaψ(PO2R-CH)Pro, were synthesized via three- (R=H) and four-step (R=CH3) procedures. The mixtures of diastereomers were evaluated as inhibitors of the human cyclophilin hCyp-18, an important peptidyl-prolyl isomerase.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2001
  • Journal title
    Tetrahedron Letters
  • Record number

    1646919

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1646919