Title of article
Opening of a vinyl aziridine with p-toluenesulfonamide under TBAF catalysis: synthesis of 3,4-diamino-3,4-dideoxy-l-chiro-inositol
Author/Authors
Paul، نويسنده , , Bernhard J and Hobbs، نويسنده , , Elizabeth and Buccino، نويسنده , , Pablo and Hudlicky، نويسنده , , Tomas، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
6433
To page
6435
Abstract
3,4-Diamino-3,4-dideoxy-l-chiro-inositol has been prepared from bromobenzene by a chemoenzymatic approach. The key chemical step was a tetrabutylammonium fluoride (TBAF) catalyzed vinyl aziridine opening employing p-toluenesulfonamide as a nucleophile, establishing the 1,2-trans relationship of the amino groups.
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1646991
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