Title of article
A new efficient synthesis of 3-(4-pyridinyl)methylindoles
Author/Authors
Zhou، نويسنده , , Ping and Li، نويسنده , , Yanfang and Meagher، نويسنده , , Kristin L and Mewshaw، نويسنده , , Richard G and Harrison، نويسنده , , Boyd L، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
7333
To page
7335
Abstract
A new efficient method for the preparation of 3-(4-pyridinyl)methylindoles has been developed. The new method involves coupling of indoles with 4-pyridinecarboxaldehyde to give 3-indolyl 4-pyridinyl methanols, which upon treatment with triethylsilane in the presence of trifluoroacetic acid afford 3-(4-pyridinyl)methylindoles in 64–76% overall yield.
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1647638
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