• Title of article

    Total synthesis of epothilone A

  • Author/Authors

    Hindupur، نويسنده , , Rama M and Panicker، نويسنده , , Bijoy and Valluri، نويسنده , , Muralikrishna and Avery، نويسنده , , Mitchell A، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    4
  • From page
    7341
  • To page
    7344
  • Abstract
    A convergent total synthesis of epothilone A (1) is described. The key steps are diastereoselective aldol condensation of aldehyde 3 to form the C6C7 bond; macrolactonization and Wadsworth–Emmons reaction of methyl ketone with phosphonate reagent 5.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2001
  • Journal title
    Tetrahedron Letters
  • Record number

    1647641