Title of article
Total synthesis of epothilone A
Author/Authors
Hindupur، نويسنده , , Rama M and Panicker، نويسنده , , Bijoy and Valluri، نويسنده , , Muralikrishna and Avery، نويسنده , , Mitchell A، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
7341
To page
7344
Abstract
A convergent total synthesis of epothilone A (1) is described. The key steps are diastereoselective aldol condensation of aldehyde 3 to form the C6C7 bond; macrolactonization and Wadsworth–Emmons reaction of methyl ketone with phosphonate reagent 5.
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1647641
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