Title of article
Radical reaction of Williams’ glycinate auxiliaries with α-amidoacrylates: synthesis of orthogonally functionalized (2R,4R)- and (2R,4S)-diaminoglutamic acids
Author/Authors
Kabat، نويسنده , , Marek M، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
7521
To page
7524
Abstract
Orthogonally functionalized (2R,4S)- and (2R,4R)-diaminoglutamic acids 10, 11, and 12, 13 were obtained in three steps starting from (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate 5, employing a radical reaction of selenide 6 with methyl 2-acetamidoacrylate 7 as a key step.
Keywords
amino acids and derivatives , selenium and compounds , diastereoselection , radicals and radical reactions
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1647878
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