Title of article
A convenient synthesis of symmetrical N,N′-dialkylureas by the reactions of 4-chloro-5H-1,2,3-dithiazol-5-one with alkylamines
Author/Authors
Chang، نويسنده , , Yong-Goo and Lee، نويسنده , , Hyi-Seung and Kim، نويسنده , , Kyongtae، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
8197
To page
8200
Abstract
Treatment of 4-chloro-5H-1,2,3-dithiazol-5-one with primary and secondary alkylamines (>2 equiv.) in CH2Cl2 at rt afforded symmetrical N,N′-disubstituted ureas in moderate to good yields. Similarly, the reactions with amino acid ester hydrochlorides in the presence of Et3N (>3 equiv.) under the same conditions gave symmetrical ureas.
Keywords
Ureas , Amines , amino acids and derivatives , dithiazoles
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1648113
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