Title of article
A convenient synthesis of 2-fluoro- and 6-fluoro-(2S,3R)-threo-(3,4-dihydroxyphenyl)serine using Sharpless asymmetric aminohydroxylation
Author/Authors
Kim، نويسنده , , In Ho and Kirk، نويسنده , , Kenneth L، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
8401
To page
8403
Abstract
Ring-fluorinated β-hydroxy α-amino methyl esters 3b,c were synthesized enantioselectively using Sharpless asymmetric aminohydroxylation. These were converted to 2-fluoro- and 6-fluoro-(2S,3R)-threo-(3,4-dihydroxyphenyl)serine 1b,c using our previously published procedure.
Keywords
2-fluoro- and 6-fluoro-(2S , 3R)-threo-(3 , Sharpless asymmetric aminohydroxylation , 4-dihydroxyphenyl)serine , regioselectivity , Enantioselectivity
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1648270
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