Title of article
Regioselective hydrolysis of diesters of (Z)- and (E)-2-methyl-butenedioic acids by PLE
Author/Authors
Schmid، نويسنده , , Rudolf and Partali، نويسنده , , Vassilia and Anthonsen، نويسنده , , Thorleif and Anthonsen، نويسنده , , Henrik W and Kvittingen، نويسنده , , Lise، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
8543
To page
8545
Abstract
Dimethyl, diethyl and dipropyl esters of (Z)- and (E)-2-methyl-butenedioic acids (citraconic and mesaconic acid) were hydrolysed by pig live esterase, PLE. For the diethyl esters the enzyme showed low regioselectivity for both the (Z)- and the (E)-isomers. However, the hydrolysis of dimethyl and dipropyl (Z)-2-methyl-butenedioic acid gave a ratio of the monoesters of 95:5 and 85:15.
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1648390
Link To Document