Title of article
Practical synthesis of the rebeccamycin aglycone and related analogs by oxidative cyclization of bisindolylmaleimides with a Wacker-type catalytic system
Author/Authors
Wang، نويسنده , , Jianji and Rosingana، نويسنده , , Miguel and Watson، نويسنده , , Daniel J and Dowdy، نويسنده , , Eric D and Discordia، نويسنده , , Robert P and Soundarajan، نويسنده , , Nachimuthu and Li، نويسنده , , Wen-Sen، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
8935
To page
8937
Abstract
Using atmospheric O2 as the stoichiometric oxidant, Pd2+/Cu2+-catalyzed oxidative cyclization of the corresponding bisindolylmaleimides provides the rebeccamycin aglycone and related indolo[2,3-a]pyrrolo[3,4-c]carbazoles in 58–88% yield. The method is operationally simple and utilizes readily prepared substrates, making the process amenable to scaleup.
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1648703
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