Title of article
Total synthesis of marine diterpenoid stolonidiol
Author/Authors
Miyaoka، نويسنده , , Hiroaki and Baba، نويسنده , , Tomohiro and Mitome، نويسنده , , Hidemichi and Yamada، نويسنده , , Yasuji، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
9233
To page
9236
Abstract
Marine dolabellane diterpenoid stolonidiol was synthesized from l-ascorbic acid. The method for this total synthesis involves formation of the bicyclo[2.2.1]heptane derivative using a diastereoselective sequential Michael reaction, formation of cyclopentane derivative by the retro-aldol reaction and construction of an 11-membered carbocyclic ring through the intramolecular Horner–Wadsworth–Emmons reaction.
Keywords
Antitumor compounds , Marine metabolites , terpenes and terpenoids
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1648933
Link To Document