Title of article
Facile preparative HPLC enantioseparation of racemic drugs using chiral stationary phases based on mono-6A-azido-6A-deoxy-perphenylcarbamoylated β-cyclodextrin immobilized on silica gel
Author/Authors
Ng، نويسنده , , Siu-Choon and Chen، نويسنده , , Lei and Zhang، نويسنده , , Li-Feng and Ching، نويسنده , , Chi-Bun، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
5
From page
677
To page
681
Abstract
Immobilized chiral stationary phases (CSP)s from mono-6A-azido-6A-deoxy-perphenylcarbamoylated β-cyclodextrin were prepared using an extended application of the Staudinger reaction. Their application in preparative enantioseparations of racemic mixtures was demonstrated using atropine, bendroflumethiazide and four β-adrenergic blocking agents under reversed phase conditions.
Keywords
Enantioseparation , HPLC , Preparative , ?-Cyclodextrin
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1649466
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