• Title of article

    The first synthesis of kaitocephalin based on the structure revision

  • Author/Authors

    Watanabe، نويسنده , , Hidenori and Okue، نويسنده , , Masayuki and Kobayashi، نويسنده , , Hiroyuki and Kitahara، نويسنده , , Takeshi، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    4
  • From page
    861
  • To page
    864
  • Abstract
    A total synthesis of kaitocephalin (2), a glutamate receptor antagonist, was accomplished employing a novel stereoselective CC bond forming reaction of a nitrone (8) and a halide (11) with zinc in aqueous solvent under sonication as a key step. The absolute configuration of kaitocephalin was confirmed to be 2R,3S,4R,7R,9S.
  • Keywords
    kaitocephalin , total synthesis , NMDA antagonist , AMPA/KA antagonist
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2002
  • Journal title
    Tetrahedron Letters
  • Record number

    1649603