Title of article
Enantioselective lipase-catalyzed reactions of methyl pipecolinate: transesterification and N-acylation
Author/Authors
Liljeblad، نويسنده , , Arto and Lindborg، نويسنده , , Jutta and Kanerva، نويسنده , , Anu and Katajisto، نويسنده , , Johanna and Kanerva، نويسنده , , Liisa T. Kanerva، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
2471
To page
2474
Abstract
The present research introduces the highly (S)-selective (E>>100) acylation at the secondary ring nitrogen of methyl pipecolinate as a novel resolution method with Candida antarctica lipase A. Catalysis by lipase B leads to reactions at the methyl ester function of the substrate in an almost non-enantioselective manner.
Keywords
RESOLUTION , Candida antarctica lipase A , Candida antarctica lipase B , Pipecolic acid , methyl pipecolinate
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1650814
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