Title of article
Asymmetric synthesis of nitrogen heterocycles by reaction of chiral β-enaminocarbonyl substrates with acrylate derivatives
Author/Authors
Agami، نويسنده , , Claude and Dechoux، نويسنده , , Luc and Hebbe، نويسنده , , Séverine، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
2521
To page
2523
Abstract
We have studied the reactivity of β-enaminoesters 1 (R2=OMe) or β-enaminoketone 1 (R2=Me), derived from (S)-phenylglycinol, with activated acrylate derivatives. Substrates 1 (R1=Me) afforded by aza-annulation oxazololactams 2 and 3,4-dihydro-2-pyridones 3. In the same conditions β-enaminoesters 1 (R1=H) furnish N-acylated oxazolidines 4.
Keywords
?-enaminoesters , oxazolactams , 3 , 4-dihydro-2-pyridones , Oxazolidines , aza-annulation
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1650842
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