Lipase-catalysed transesterification in ionic liquids and organic solvents: a comparative study

The lipase-catalysed transesterifications of 2-hydroxymethyl-1,4-benzodioxane in two different ionic liquids, 1-butyl-3-methylimidazolium hexafluorophosphate, [bmim]PF6 and 1-butyl-3-methylimidazolium tetrafluoroborate, [bmim]BF4 and different organic solvents was studied. The hydrophobic and hydrophilic properties of ionic liquids and organic solvents do influence the lipase activity as illustrated from the results. The influence of the ionic liquid as an additive in an organic solvent on this reaction has been demonstrated. The enzymes in ionic liquids in combination can be recycled for several runs without substantial diminution in the lipase activity.